SusMer · Website previewPrecision Chain / Team review

P4HB biomaterials for medical devices

A new route
to P4HB.

SusMerFlex™ — chemically synthesized P4HB
for medical-device manufacturers.

P4HB / illustrative molecular structure

The material. The method.

P4HB, through
chemical synthesis.

SusMerFlex™ is SusMer’s P4HB raw material, produced through ring-opening polymerization. It offers a chemical synthesis route to a polymer already used in absorbable sutures and hernia meshes.

P4HB repeating unitOxygen bonded to three methylene groups and a carbonyl carbon, repeated n times.OCH₂CH₂CH₂COn
P4HBPoly(4-hydroxybutyrate) · repeating unit

Designed around device requirements.

Our development work brings together molecular-weight selection, material characterization and process scale-up. We work with device manufacturers to evaluate the material against their application and processing requirements.

Start a technical conversation
Material
Poly(4-hydroxybutyrate)
Route
Ring-opening polymerization
Starting forms
Pellets & films

Medical-device applications

From polymer
to medical device.

Sutures and hernia meshes put P4HB to work in soft-tissue repair. SusMer focuses on the raw material and the requirements of the manufacturers building those devices.

The people behind SusMer

Polymer science.
Medical-device experience.

Founded to commercialize chemistry developed at Colorado State University, SusMer brings scientists and industry operators together in Fort Collins, Colorado.

Dr. Ravikumar Ramegowda

Dr. Ravikumar Ramegowda

Co-founder, President & CTO

Co-founded SusMer in 2014. His work in monomers, catalysts and ring-opening polymerization connects polymer chemistry with material and process development.

Prof. Dr. Eugene Chen

Prof. Dr. Eugene Chen

Co-founder & Scientific Advisor

University Distinguished Professor at Colorado State University. His research in polymer chemistry forms the scientific foundation of SusMer’s approach.

Todd Blair

Todd Blair

Chief Executive Officer

Brings more than 20 years of medical-device commercial and corporate development experience, with past roles at Johnson & Johnson, Confluent Medical and Heraeus Medical.

Jake Larger

Jake Larger

Chief Financial & Operating Officer

Joined SusMer in 2019. Leads finance and operations, supporting commercialization and relationships with medical-device manufacturers and development partners.

Work with SusMer

Start with your device.
Build a material program.

We work with medical-device OEMs, contract manufacturers and research partners to define the material evaluation and development work an application needs.

Define the requirements

Share your device category, processing route, material form and target properties.

Evaluate the material

Discuss available grades, sample quantities and the testing needed to assess fit.

Plan the next stage

Align on characterization, process development and scale-up priorities.

Before we begin

Before your
material evaluation.

What is SusMerFlex™?

SusMerFlex™ is SusMer’s chemically synthesized P4HB raw material for medical-device development. It is a material platform, not a finished suture or surgical mesh.

How is it made?

SusMer uses ring-opening polymerization as an alternative to microbial fermentation. Development work focuses on molecular-weight selection, material characterization and manufacturing scale-up.

What forms and quantities are available?

Pellets and films are the starting material formats. Contact the team to confirm current grades, evaluation quantities and timing for your program.

How do we evaluate it for our device?

Start with the intended application and processing route. The team can discuss a material evaluation plan and available characterization information. Suitability, processing compatibility and biological safety need to be assessed for the specific finished device.

For OEMs, CMOs & CDMOs

Let’s talk about
your application.

Discuss SusMerFlex™ for your device,
your process and your development timeline.

Email the SusMer team

contact@susmer.com

Website preview for SusMer team review. Team titles and final copy remain subject to confirmation. Application models are illustrative. Portraits have been edited for a consistent background and crop.